Association of adipokines and adhesion molecules with indicators of obesity in women undergoing mammography screening
![Thumbnail](/bitstream/handle/10183/109963/000867399.pdf.jpg?sequence=3&isAllowed=y)
Visualizar/abrir
Data
2012Autor
Tipo
Assunto
Abstract
Background: The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis. Objective: To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening. Design: Transversal stu ...
Background: The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis. Objective: To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening. Design: Transversal study. Subjects: One hundred and forty-five women over 40-years old participated in this study. Results: In 39.3% of cases the BMI was above 30 kg/m2; 46.9% had hypertension, 14.5% had type 2 Diabetes Mellitus, 31.7% had dyslipidemia and 88.3% presented a waist-to-hip ratio ≥ 0.8. A linear correlation was found between serum levels of PAI-1 and triglycerides, between serum levels of PAI-1 and WHR and between serum levels of VCAM-1 and BMI. Conclusion: We found a high prevalence of obesity and metabolic syndrome. PAI-1 and VCAM-1 levels were correlated with clinical indicators of obesity and overweight. ...
Contido em
Nutrition & metabolism. London. Vol. 9 (2012), 16 p.
Origem
Estrangeiro
Coleções
-
Artigos de Periódicos (39351)Ciências da Saúde (10587)
-
Artigos de Periódicos (39351)Ciências Biológicas (3068)
Este item está licenciado na Creative Commons License
![](/themes/Mirage2Novo//images/lume/cc.png)